Below links direct the interested reader into further articles and studies conserning different issues affecting our and our pets health.

http://www.cababstractsplus.org/abstracts/Abstract.aspx?AcNo=20043046002 Objective - To evaluate viability of a probiotic strain of Lactobacillus acidophilus in a dry dog food, determine its ability to survive transit through the gastrointestinal tract and populate the colon, and assess its effects on intestinal and systemic parameters.

http://www.ncbi.nlm.nih.gov/pubmed/15027683 OBJECTIVE: To evaluate viability of a probiotic strain of Lactobacillus acidophilus in a dry dog food, determine its ability to survive transit through the gastrointestinal tract and populate the colon, and assess its effects on intestinal and systemic parameters.

http://avmajournals.avma.org/doi/abs/10.2460/ajvr.67.6.1005—Objective - To evaluate the effect of dietary supplementation with the probiotic strain Lactobacillus acidophilus DSM13241 in healthy adult cats.

http://cat.inist.fr/?aModele=afficheN&cpsidt=17822412 Objective-To evaluate the effect of dietary supplementation with the probiotic strain Lactobacillus acidophilus DSM13241 in healthy adult cats.

http://www.biomedexperts.com/Abstract.bme/16740094/Effects_of_Lactobacillus_acidophilus_DSM13241_as_a_probiotic_in_healthy_adult_cats. Effects of Lactobacillus acidophilus DSM13241 as a probiotic in healthy adult cats.

http://direct.bl.uk/bld/PlaceOrder.do?UIN=189028075&ETOC=RN&from=searchengine Effects of Lactobacillus acidophilus DSM13241 as a probiotic in healthy adult cats.

http://www.petfoodindustry-digital.com/petfoodindustry/200608/?pg=34 Effects of Lactobacillus DSM13241 in adult cats

http://jn.nutrition.org/cgi/content/full/134/8/2022S Bacteria in the Gut: Friends and Foes and How to Alter the Balance

http://www.informaworld.com/smpp/content~content=a791165646~db=all~jumptype=rss Effects of a probiotic Lactobacillus acidophilus strain on feed tolerance in dogs with non-specific dietary sensitivity

http://www.ajcn.org/cgi/content/full/86/3/542 Science is beginning to understand how genetic variation and epigenetic events alter requirements for, and responses to, nutrients (nutrigenomics).

http://www.epidna.com/showabstract.php?pmid=17213870&redirect=yes&terms=epigenetics+nutrigenomics Pharmacogenomics and nutrigenomics: synergies and differences. The aim of both disciplines is to individualize or personalize medicine and food and nutrition, and ultimately health, by tailoring the drug or the food to the individual genotype.

http://www.epidna.com/showabstract.php?pmid=19261726 Epigenetic mechanisms for nutrition determinants of later health outcomes. Epigenetic marking on genes can determine whether or not genes are expressed.

http://www.ubic-consulting.com/template/fs/documents/Nutrition/Individualnutrition-Nutrigenomics-market.pdf NUTRIGENOMICS – INDIVIDUAL NUTRITION - WHAT FUTURE ?

http://www.epidna.com/showabstract.php?pmid=15956042 The Genome Health Clinic and Genome Health Nutrigenomics concepts: diagnosis and nutrition. The evidence of a direct link between increased genome/epigenome damage and elevated risk for adverse health outcomes during the various stages of life, such as infertility, foetal development and cancer is becoming increasingly stronger.

http://www.iom.edu/Object.File/Master/36/707/Nutrigenomics%20and%20Epigenetics.pdf Nutrigenomics and epigenetics - Public Health Perspective

http://ezinearticles.com/?id=1236231 Cancer, Epigenetics, and Nutrigenomics - How Food Affects Your Cancer Genes

http://www.univie.ac.at/nutrigenomics/downloads/EF%20Nutrigenomics.pdf Emerging focus Nutrigenomics

http://www.ajcn.org/cgi/reprint/86/3/542.pdf Nutrigenomics and metabolomics will change clinical nutrition and public health practice.

http://www.cosmeticsdatabase.com/ingredient.php?ingred06=700740&refurl=/product.php?prod_id=67003&&nothanks=1 BHA - Known immune system toxicant, may cause cancer, is neurotoxic, cause developemental and reproductive toxicity, biochemical or cellular level changes.

http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=PureSearch&db=pubmed&term=(25013-16-5[RN]%20OR%20%22BHA%22[TW]%20OR%20%22BUTYLATED%20HYDROXYANISOLE%22[TW]%20OR%20%22BUTYLHYDROXYANISOL%22[TW]%20OR%20%22(1%2C1-DIMETHYLETHYL)-4-METHOXYPHENOL%22[TW]%20OR%20%22PHENOL%2C%20(1%2C1-DIMETHYLETHYL)-4-METHOXY-%22[TW]%20OR%20%22(1%2C1-DIMETHYLETHYL)-4-METHOXY-%20PHENOL%22[TW]%20OR%20%22BHA%22[TW]%20OR%20%221%2C1-DIMETHYLETHYL-4-METHOXYPHENOL%22[TW]%20OR%20%22BUTYLATED%20HYDROXYANISOLE%3B%20BHA%22[TW]%20OR%20%22BUTYLHYDROXYANISOL%22[TW]%20OR%20%22PHENOL%2C%20(1%2C1DIMETHYLETHYL)4METHOXY%22[TW]%20OR%20%22TERT-BUTYL-4-METHOXYPHENOL%22[TW]%20)%20%20AND%20(*toxic*%20OR%20cosmet*%20OR%20derm*%20OR%20irritation%20OR%20sensiti*%20OR%20%22personal%20care%20products%22%20OR%20skin%20OR%20gavage%20OR%20mutagen*%20OR%20carcinogen*%20OR%20%22biological%20activity%22)

List of studies, some indicating BHA/BHT potentially being detrimental for health

http://cat.inist.fr/?aModele=afficheN&cpsidt=3463680 Inhibition of prostaglandin H synthase by ASA in cultures treated with TBHQ decreased the oxidation ratio significantly, confirming the significance of this enzyme system in the mechanism of toxicity of BHA

http://chemistry.about.com/library/weekly/aa082101a.htm BHA and BHT Why are BHA and BHT in foods? Are they safe?

http://cat.inist.fr/?aModele=afficheN&cpsidt=3401441 The severity of hyperplasia and inflammation in both forestomach and glandular stomach appeared to increase gradually with continued BHA administration

http://en.wikipedia.org/wiki/DNA_repair DNA repair refers to a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome.

http://en.wikipedia.org/wiki/Mutagen In biology, a mutagen (Latin, literally origin of change) is a physical or chemical agent that changes the genetic material (usually DNA) of an organism and thus increases the frequency of mutations above the natural background level. As many mutations cause cancer, mutagens are typically also carcinogens.

http://www.veterinarypartner.com/Content.plx?P=A&C=&A=516&SourceID= Signs, Symptoms and Diagnosis of Hyperthyroidism HYPERTHYROIDISM IS GENERALLY A DISEASE OF OLDER CATS.

http://www.alkalizeforhealth.net/Ldnadamage.htm DNA Damage from Sucralose, Cyclamate, Saccharin, Aspartame, Food Dyes, Preservatives (BHA, BHT), Fungicides and Other Food Additives

http://cancerres.aacrjournals.org/cgi/reprint/54/7_Supplement/1895s.pdf Reactive Oxygen-dependent DNA Damage Resulting from the Oxidation of Phenolic Compounds by a Copper-Redox Cycle Mechanism1

https://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=B1378|ALDRICH&N5=SEARCH_CONCAT_PNO|BRAND_KEY&F=SPEC Butylated hydroxytoluene (BHT) is a phenolic antioxidant. It has been shown to inhibit lipid peroxidation. It causes lung injury and promotes tumors in mice

http://www.agls.uidaho.edu/foodtox/lectures/lecture14/L14-Toxicology%20of%20Selected%20Food%20Additives.pdf Toxicology of Selected
Food Additives - • Liver enlargement • Stored in fat – Slowly excreted-BHT • Slow DNA/RNA synthesis • Reduce cell growth in vitro • Cause chromosomal anomalies in vitro – Conflicting studies • Idiosyncratic sensitivity

http://books.google.fi/books?id=6mGmxYqqiREC&pg=PA108&lpg=PA108&dq=epigenetics+bha&source=bl&ots=vM5io0VTea&sig=YyNmAb4SlFMSTSWdY5Q_zb3lF-Q&hl=fi&ei=VnFUSqnpFJmwnQP-kbAF&sa=X&oi=book_result&ct=result&resnum=1#v=onepage&q=&f=false Food additive toxicology - Joseph A. Maga, Anthony T. Tu

http://www.scribd.com/doc/13104162/ Nutrigenomics-Emerging-Face-of-Molecular-Nutrition-to-Improve-Animal-Health-and-Production

http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1000185 Omega-3 Fatty Acids and Inflammation: Novel Interactions Reveal a New Step in Neutrophil Recruitment